PatientInitials or Identified Number Mr.AS 60 years old. RelevantClinical History and Physical Exam Patientwith stable angina pectoris CCS II. Risk factors are dyslipidemia and formersmoker. Post PCI 1 DES (2.5 x 24 mm) in 2022 at diagonal branch in                the district`shospital. The haemodynamicin the preparation room were 110/70 mmHg and HR 80 bpm with no abnormalities onthe physical examinations.

 -        ECG: Normal Sinus Rhythm withinnormal limit.-        Blood Count : Hemoglobin level of 12.9 g/dL,White Blood Cell count of 8760 /µL,Platelet count 241.000 /µL, Urea level 21.9mg/dL,                                             Creatinine level 1.07 mg/dL, eGFR 80 ml/menit/1.73m² ,Cholesterol 169 mg/dl, LDL 110 mg/dl, HDL 34 mg/dl, A1C 6%. 

AngiographyResult             LeftMain       : Normal.            LAD               :Proximal stenosis 70-80% at bifurcatio Diagonal 2 (Medina 1-1-1)                                     With ISR type IB proximal Diagonal 2.            LCx               :Non dominant, normal.            RCA              :Dominant, normal.

Firstly guided LCA with XB 3.5/6F. Then continued double wiring with Workhorse wire to distal LADand distal Side Branch (SB). Predilatationwith NC balloon 2.5 x 15 mm from mid to proximal LAD and continued to proximal SB. Implanted DES 3.0 x 28 mm but could not pass the proximalLAD. Rewiring with a new Workhorse   wire to SB and perfomed buddy wire tothe distal LAD but stent still could not pass the LAD and continued predilatation again with NC balloon 2.5 x 15 mm.Implanted DES 3.0 x 28 mm and post dilatation with stent balloon at the proximal LAD. Buddy wire was removed and then exchange wire to SBand to LAD,            followed Opening Struts with Semi-compliant balloon 2.0 x 15 mm atproximal SB then perfomed kissing balloon with NC balloon 2.5 x 15 mm atproximal SB and  stent balloon 3.0 x 28 mm at proximal LAD instent. POT wasperformed in the proximal instent LAD with NC 3.25 x 12 mm. Followed rewiring the SB and LAD thenDCB implantation2.75 x 20 mm inflated for 1 minute at proximal SB.Perfomed with final kissing balloon with DCB balloon 2.75 x 20 mm in proximal SBand stent balloon 3.0 x 28 mm balloon in proximal LAD instent. Final POTwas  performed with NC balloon 3.25 x 12 mm to proximal LAD instent but couldnot pass proximal LAD, so did the buddy wire again to distal LAD then continued with    final POTwith NC balloon 3.25 x 12 mm. The final angiography results were good with TIMI 3 flow,no dissection and no residual stenosis.

Provisional Side Branch stentingstrategy is the default approach for the majority of bifurcation lesions, butoutcomes of SB is suboptimal.The Drug Coated Balloon (DCB) improving SB outcomesattracts an increasing attention, the hybrid strategy facilitates treatment ofDCB andstent for bifurcation lesions. This case demonstrated the hybrid strategy in bifurcation lesion with DCB.