Transcatheter aortic valve replacement is a standard treatment in patients with severe aortic valve stenosis. Due to a unique characteristic of Thai population, data regarding to safety and efficacy of TAVR in Thai population had not been well studied. This study described clinical characteristic and outcomes of TAVR at Ramathibodi hospital.

All patients underwent TAVR in Ramathibodi hospital from December 2011 to May 2019 were retrospectively reviewed. Baseline patient characteristic, 30 days and 1year outcome including survival rate and major complication were described. Doppler echocardiographic parameter including mean AV pressure gradient and AVA were analyzed pre- and post- TAVR. The major outcomes were compared to contemporary STS/ACC TVT 2016 registry.

A total of 105 cases patients underwent TAVR in Ramathibodi hospital were recorded and analyzed. Mean age was 82±6.2 years and 65% were female. Most of the patient were at NYHA class 3 (61.9%). AV MPG and AVA were 49.6±11.9mmHg and 0.6±0.2 m² respectively. TAVR success rate was 98.1%. When compared to 2016 STS/ACC TVT registry, most patients in our report were Asian (95.2% versus 1.1%) and female gender was predominant (65.7% versus 49%) while Age and STS score were comparable. 30 day outcomes including dead, new PPM, AV re-intervention and stroke were not significantly different except significant PVL (>2+) was lower in our report (1.9% versus 6.9%, p=0.007).

TAVR procedure is safe and effective for the treatment of patients with severe aortic valve stenosis. Our data is comparable to contemporary western registry. Overtime, procedure was done more frequently, patient STS score were lower, transfemoral was preferred and hospital time was shortened.